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S-Adenosylmethionine (SAM-e)

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S-Adenosylmethionine (SAM-e) is a biologically active methyl-donor compound supplied in stabilized salt forms for mood, joint and healthy-aging formulations.

GoodNutrition supplies this ingredient for supplement, functional food and personal care manufacturers. We support bulk purchasing with specification review, sample evaluation and export documentation for ongoing B2B supply projects.

Please confirm assay, appearance, solubility, packaging format and intended application with our team before order placement so the material profile matches your formula and market requirements.

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COA / MSDS documents

COA information for this ingredient is loading. If the document does not appear, please contact GoodNutrition for the current batch COA and MSDS.

GoodNutrition supplies botanical extracts and nutraceutical ingredients for supplement, functional food and personal care manufacturers. Contact us to confirm specification, assay, solubility, sample availability, MOQ, packaging and current lead time for this item.

We support B2B purchasing with COA documentation, production coordination and repeat-order planning for wholesale ingredient projects.

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Document Support

Need COA, MSDS, packaging or MOQ details for this ingredient?

Share the target specification, dosage form, market and estimated quantity with our team. We can help coordinate document review, sample planning, packaging discussion and quotation support faster for supplement and functional food projects.

Specification reviewAssay, appearance, solubility and application fit for your formulation direction.
Packaging & MOQDiscuss sample size, bulk packing format and commercial quantity planning with our sales team.
COA / MSDS requestUseful for evaluation, internal QA checks and cross-team approval before commercial orders.

Certification and Documentation Support

Good Nutrition Bio supports supplier qualification with ISO 9001 quality management, ISO 22000 food safety management, KOF-K Kosher, Halal, USDA Organic and EU Organic documentation where applicable. Buyers should confirm the current certificate scope, issuing body, validity dates and product applicability for each project.

ISO 9001 ISO 22000 KOF-K Kosher Halal USDA Organic EU Organic

Good Nutrition Bio supplies bulk S-Adenosylmethionine (SAM-e) for dietary supplement brands, contract manufacturers and functional nutrition developers. SAM-e is a biologically active methyl-donor compound supplied in stabilized salt forms for mood, joint and healthy-aging formulations.

For B2B sourcing, SAM-e should not be compared by total powder weight alone. Buyers should confirm the active SAM-e basis, salt form, active/inactive isomer ratio, degradation profile, moisture control, packaging system and batch COA before approving a commercial lot.

Product Specification

Product NameS-Adenosylmethionine (SAM-e)
Material IdentitySAM-e stabilized salt; exact counterion batch specific
AppearanceWhite to off-white crystalline powder
Available SpecificationTotal SAM-e, active SAM-e basis, salt form, isomer ratio and degradation products, batch specific
ApplicationCapsules, protected capsules, enteric-coated tablets and low-moisture powder systems
DocumentsCOA, specification sheet and supporting quality documents available by request

Why Buyers Choose Good Nutrition Bio

  • Bulk SAM-e ingredient supply for nutraceutical and supplement manufacturing projects
  • Specification support for active basis, salt form, isomer ratio and degradation control
  • Batch-specific COA review for assay, water content and safety parameters
  • Sample support and moisture-barrier packaging discussion for qualified B2B projects

Formulation & Handling

  • Use low-moisture processing and moisture-barrier packaging
  • Evaluate protected capsules or enteric-coated tablets for sensitive finished products
  • Calculate label claim from active SAM-e rather than total stabilized salt weight
  • Control temperature, humidity and exposure time during blending and filling

Quality Parameters to Review

  • SAM-e assay on an active basis and confirmed salt identity
  • Active/inactive isomer ratio and degradation products
  • Water content, residual solvents, heavy metals and microbiological limits
  • Packaging suitability, shelf-life support and destination-market requirements

Final suitability should be confirmed against the agreed product specification, batch COA, destination-market requirements and the buyer’s finished-product validation.

B2B Purchasing Details

For bulk S-Adenosylmethionine (SAM-e) purchasing, Good Nutrition Bio can support specification confirmation, current batch COA review, sample evaluation and export documentation before commercial orders.

  • Documents: specification sheet, batch COA and available quality documents can be shared for review.
  • Key checks: buyers commonly review active SAM-e basis, salt form, isomer ratio, degradation products, water content, heavy metals and microbiological limits.
  • Packaging: moisture-barrier packaging, low-temperature handling and fast resealing after opening; final packing can be confirmed by order quantity and destination requirements.
  • MOQ and lead time: confirmed by current inventory, specification and shipping destination.

Request a quote or sample or contact our team with your target specification, quantity and destination market.

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Buyer FAQ

What should buyers verify when sourcing SAM-e?

Buyers should verify active SAM-e assay, salt identity, active/inactive isomer ratio, degradation products, water content, residual solvents, heavy metals, microbiological limits and the batch COA.

Can Good Nutrition Bio provide SAM-e samples and COA?

Sample and COA support can be provided for qualified B2B projects. Buyers can share the target salt form, dosage form, destination market and estimated volume for specification discussion.

How should SAM-e be formulated?

SAM-e is sensitive to moisture, heat and degradation, so low-moisture processing, suitable excipients, protected dosage forms and moisture-barrier packaging should be evaluated before scale-up.

Is SAM-e available as a bulk ingredient?

Yes. Good Nutrition Bio supplies SAM-e as a bulk ingredient for supplement brands, contract manufacturers and functional nutrition developers.